| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
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| Ligand | BDBM50097734 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_48265 |
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| IC50 | 24000±n/a nM |
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| Citation |  Dziadulewicz, EK; Walpole, CS; Snell, CR; Wrigglesworth, R; Hughes, GA; Beattie, D; Wood, JN; Beech, MM; Coote, PR Design of non-peptide CCK2 and NK1 peptidomimetics using 1-(2-nitrophenyl)thiosemicarbazide as a novel common scaffold. Bioorg Med Chem Lett11:705-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin/cholecystokinin type B receptor |
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| Name: | Gastrin/cholecystokinin type B receptor |
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| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49196.59 |
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| Organism: | MOUSE |
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| Description: | Cholecystokinin A CCKBR MOUSE::P56481 |
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| Residue: | 453 |
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| Sequence: | MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGL
ISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCY
VQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANT
WRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPR
ARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
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| BDBM50097734 |
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| n/a |
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| Name | BDBM50097734 |
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| Synonyms: | 1-(2-nitrophenyl)thiosemicarbazide analogue | CHEMBL159623 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N6O6S2 |
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| Mol. Mass. | 554.598 |
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| SMILES | OC(=O)c1ccc(NC(=[SH+])[N-]Nc2ccc(cc2[N+]([O-])=O)S(=O)(=O)NCCc2c[nH]c3ccccc23)cc1 |
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| Structure | 
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