| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Rev |
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| Ligand | BDBM50099377 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_79479 |
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| Kd | 160±n/a nM |
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| Citation |  Tok, JB; Dunn, LJ; Des Jean, RC Binding of dimeric aminoglycosides to the HIV-1 rev responsive element (RRE) RNA construct. Bioorg Med Chem Lett11:1127-31 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Protein Rev |
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| Name: | Protein Rev |
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| Synonyms: | Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev |
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| Type: | PROTEIN |
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| Mol. Mass.: | 13078.11 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_79479 |
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| Residue: | 116 |
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| Sequence: | MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERIL
GTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
|
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| BDBM50099377 |
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| n/a |
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| Name | BDBM50099377 |
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| Synonyms: | Aminoglycoside dimer analogue | CHEMBL3037952 | Neo-Tob dimer | Tobramycin-Neomycin |
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| Type | Small organic molecule |
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| Emp. Form. | C49H97N11O22S4 |
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| Mol. Mass. | 1320.615 |
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| SMILES | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CSCCOCCSSCCOCCSC[C@H]4O[C@@H](O[C@H]5[C@H](O)[C@@H](N)C[C@@H](N)[C@@H]5O[C@H]5O[C@H](CN)[C@@H](O)[C@H](O)[C@H]5N)[C@H](O)[C@@H]4O[C@H]4OC(CN)[C@@H](O)[C@H](O)[C@H]4N)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O |r| |
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| Structure | 
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