| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50108390 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_62248 (CHEMBL675475) |
|---|
| Ki | 842±n/a nM |
|---|
| Citation |  Iriepa, I; Villasante, FJ; Gálvez, E; Labeaga, L; Innerarity, A; Orjales, A Synthesis and pharmacology of isoquinuclidine derivatives as 5-HT(3) ligands. Bioorg Med Chem Lett12:189-92 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50108390 |
|---|
| n/a |
|---|
| Name | BDBM50108390 |
|---|
| Synonyms: | 4-Amino-5-chloro-2-methoxy-N-(2-methyl-2-aza-bicyclo[2.2.2]oct-5-yl)-benzamide | CHEMBL56994 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H22ClN3O2 |
|---|
| Mol. Mass. | 323.818 |
|---|
| SMILES | COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC1CN2C |TLB:12:13:20.19:17.16,21:20:13.14:17.16| |
|---|
| Structure | 
|
|---|
Search and Browse
