| Reaction Details |
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 | Report a problem with these data |
| Target | Thermolysin |
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| Ligand | BDBM50121452 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210401 |
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| Ki | 11±n/a nM |
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| Citation |  Kim, J; Glekas, A; McN Sieburth, S Silanediol-based inhibitor of thermolysin. Bioorg Med Chem Lett12:3625-7 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thermolysin |
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| Name: | Thermolysin |
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| Synonyms: | THER_BACTH | npr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60097.54 |
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| Organism: | Bacillus thermoproteolyticus |
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| Description: | ChEMBL_1468794 |
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| Residue: | 548 |
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| Sequence: | MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEEL
VYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDG
TLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVY
VNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVG
VGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDA
PAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQ
TFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEI
GEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGG
THYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQ
AFDAVGVK
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| BDBM50121452 |
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| n/a |
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| Name | BDBM50121452 |
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| Synonyms: | (S)-2-{(S)-2-[(Benzyloxycarbonylamino-methyl)-hydroxy-phosphonium-methyl]-4-methyl-pentanoylamino}-4-methyl-pentanoic acid anion |
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| Type | Small organic molecule |
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| Emp. Form. | C22H33N2O7P |
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| Mol. Mass. | 468.4815 |
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| SMILES | CC(C)C[C@H](CP(O)([O-])=CNC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C([O-])=O |
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| Structure | 
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