| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
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| Ligand | BDBM50133800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_41922 |
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| IC50 | 500±n/a nM |
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| Citation |  Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Design and synthesis of novel CCR3 antagonists. Bioorg Med Chem Lett13:3597-600 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| C-C chemokine receptor type 3 |
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| Name: | C-C chemokine receptor type 3 |
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| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41053.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51677 |
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| Residue: | 355 |
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| Sequence: | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
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| BDBM50133800 |
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| n/a |
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| Name | BDBM50133800 |
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| Synonyms: | 1-{1-[1-(3,4-Dichloro-benzyl)-piperidin-4-ylmethyl]-2-methyl-propyl}-3-(3,4,5-trimethoxy-phenyl)-urea | CHEMBL420709 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37Cl2N3O4 |
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| Mol. Mass. | 538.506 |
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| SMILES | COc1cc(NC(=O)NC(CC2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)C(C)C)cc(OC)c1OC |
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| Structure | 
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