| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50124119 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29472 |
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| Ki | 820±n/a nM |
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| Citation |  Lim, MH; Kim, HO; Moon, HR; Lee, SJ; Chun, MW; Gao, ZG; Melman, N; Jacobson, KA; Kim, JH; Jeong, LS Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands. Bioorg Med Chem Lett13:817-20 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50124119 |
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| n/a |
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| Name | BDBM50124119 |
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| Synonyms: | 5-{2-chloro-6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-3-fluoro-4-hydroxy-N-methyltetrahydrofuran-2-carboxamide | CHEMBL436255 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClFIN6O3 |
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| Mol. Mass. | 546.722 |
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| SMILES | CNC(=O)C1OC(C(O)C1F)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc12 |
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| Structure | 
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