| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A3 |
|---|
| Ligand | BDBM50124120 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_32003 |
|---|
| Ki | 326±n/a nM |
|---|
| Citation |  Lim, MH; Kim, HO; Moon, HR; Lee, SJ; Chun, MW; Gao, ZG; Melman, N; Jacobson, KA; Kim, JH; Jeong, LS Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands. Bioorg Med Chem Lett13:817-20 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A3 |
|---|
| Name: | Adenosine receptor A3 |
|---|
| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36197.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P0DMS8 |
|---|
| Residue: | 318 |
|---|
| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
|
|
|
|---|
| BDBM50124120 |
|---|
| n/a |
|---|
| Name | BDBM50124120 |
|---|
| Synonyms: | 2-[2-chloro-6-(methylamino)-9H-purin-9-yl]-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol | CHEMBL168843 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H13ClFN5O3 |
|---|
| Mol. Mass. | 317.704 |
|---|
| SMILES | CNc1nc(Cl)nc2n(cnc12)C1OC(CO)C(F)C1O |
|---|
| Structure | 
|
|---|
Search and Browse
