| Reaction Details |
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 | Report a problem with these data |
| Target | Prostacyclin receptor |
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| Ligand | BDBM50125417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158022 |
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| Ki | >13000±n/a nM |
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| Citation |  Billot, X; Chateauneuf, A; Chauret, N; Denis, D; Greig, G; Mathieu, MC; Metters, KM; Slipetz, DM; Young, RN Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg Med Chem Lett13:1129-32 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostacyclin receptor |
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| Name: | Prostacyclin receptor |
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| Synonyms: | PGI receptor | PI2R_HUMAN | PRIPR | PTGIR | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor | Prostanoid IP receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40968.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The membranes prepared from human platelet were used in binding assay. |
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| Residue: | 386 |
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| Sequence: | MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
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| BDBM50125417 |
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| n/a |
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| Name | BDBM50125417 |
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| Synonyms: | 7-[(R)-2-((E)-3-Hydroxy-4-phenyl-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid | CHEMBL14359 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29NO4 |
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| Mol. Mass. | 359.4593 |
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| SMILES | OC(Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O |
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| Structure | 
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