| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent creatine transporter 1 |
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| Ligand | BDBM50047005 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49277 |
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| Ki | 200000±n/a nM |
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| Citation |  Geldenhuys, WJ; Lockman, PR; McAfee, JH; Fitzpatrick, KT; Van der Schyf, CJ; Allen, DD Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter. Bioorg Med Chem Lett14:3085-92 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium- and chloride-dependent creatine transporter 1 |
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| Name: | Sodium- and chloride-dependent creatine transporter 1 |
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| Synonyms: | CHOT1 | CT1 | Creatine transporter | Creatine transporter 1 | SC6A8_RAT | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Solute carrier family 6 member 8 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 70632.63 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_49276 |
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| Residue: | 635 |
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| Sequence: | MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMD
FIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGS
INVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPD
CVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLL
ACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKL
GSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVF
SILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFV
GVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASG
TTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVV
YYKPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWG
LHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
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| BDBM50047005 |
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| n/a |
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| Name | BDBM50047005 |
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| Synonyms: | 1-Aza-bicyclo[2.2.2]octan-3-ol | 1-Aza-bicyclo[2.2.2]octan-3-ol (3-quinuclidinol) | 3-hydroxy-1-azoniabicyclo[2.2.2]octane | CHEMBL276310 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H13NO |
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| Mol. Mass. | 127.1842 |
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| SMILES | OC1CN2CCC1CC2 |THB:0:1:7.8:5.4,(6.92,.2,;7.84,-.7,;6.97,-1.64,;7.02,-3.14,;8.8,-4.11,;9.62,-2.84,;7.9,-1.89,;6.04,-2.81,;5.27,-4.16,)| |
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| Structure | 
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