| Reaction Details |
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 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
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| Ligand | BDBM50027042 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_98520 (CHEMBL856600) |
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| Ki | 890±n/a nM |
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| Citation |  Rich, DH; Moon, BJ; Harbeson, S Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes. J Med Chem27:417-22 (1984) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytosol aminopeptidase |
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| Name: | Cytosol aminopeptidase |
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| Synonyms: | AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56171.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507539 |
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| Residue: | 519 |
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| Sequence: | MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD
KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN
IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS
GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI
EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD
LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
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| BDBM50027042 |
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| n/a |
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| Name | BDBM50027042 |
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| Synonyms: | 3-Amino-2-hydroxy-5-methyl-hexanoic acid {2-methyl-1-[2-methyl-1-(3-methyl-butylcarbamoyl)-propylcarbamoyl]-propyl}-amide | CHEMBL3143143 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H44N4O4 |
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| Mol. Mass. | 428.6092 |
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| SMILES | CC(C)CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](O)[C@@H](N)CC(C)C)C(C)C)C(C)C |r| |
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| Structure | 
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