| Reaction Details |
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 | Report a problem with these data |
| Target | Prostacyclin synthase |
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| Ligand | BDBM50025953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157785 |
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| IC50 | 100000±n/a nM |
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| Citation |  Ford, NF; Browne, LJ; Campbell, T; Gemenden, C; Goldstein, R; Gude, C; Wasley, JW Imidazo[1,5-a]pyridines: a new class of thromboxane A2 synthetase inhibitors. J Med Chem28:164-70 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostacyclin synthase |
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| Name: | Prostacyclin synthase |
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| Synonyms: | CYP8 | CYP8A1 | PTGIS | PTGIS_HUMAN | Prostaglandin I2 synthase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57109.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_157785 |
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| Residue: | 500 |
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| Sequence: | MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEK
HGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDE
KARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTL
YGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKL
LSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLL
KNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITRE
VVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDF
YKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSR
YGFGLMQPEHDVPVRYRIRP
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| BDBM50025953 |
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| n/a |
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| Name | BDBM50025953 |
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| Synonyms: | 6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid | CGS-13080 | CHEMBL48092 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2O2 |
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| Mol. Mass. | 232.2783 |
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| SMILES | OC(=O)CCCCCc1cccc2cncn12 |
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| Structure | 
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