| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50018159 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_27639 |
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| Ki | 2500±n/a nM |
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| Citation |  Daly, JW; Padgett, W; Shamim, MT; Butts-Lamb, P; Waters, J 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors. J Med Chem28:487-92 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_CAVPO | ADENOSINE A2 | ADORA2A | Adenosine A2a receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44955.08 |
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| Organism: | GUINEA PIG |
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| Description: | ADENOSINE A2 0 GUINEA PIG::P46616 |
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| Residue: | 409 |
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| Sequence: | MSSSVYITVELVIAVLAILGNVLVCWAVWINSNLQNVTNYFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLTITIDRYIAIRIPLRYNGLVTCTRAKG
IIAICWVLSFAIGLTPMLGWNNCSQPKGDKNHSESCDEGQVTCLFEDVVPMNYMVYYNFF
AFVLVPLLLMLGIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHPAKSLAIIVGLFA
LCCLPLNIINCFTFFCPECDHAPPWLMYLTIILSHGNSVVNPLIYAYRIREFRQTFRKII
RSHILRRRELFKAGGTSARASAAHSPEGEQVSLRLNGHPPGVWANGSALRPEQRPNGYVL
GLVSGRSAQRSHGDASLSDVELLSHEHKGTCPESPSLEDPPAHGGAGVS
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| BDBM50018159 |
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| n/a |
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| Name | BDBM50018159 |
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| Synonyms: | 4-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzoic acid | 8-(4-Carboxyphenyl)theophylline | CHEMBL11048 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N4O4 |
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| Mol. Mass. | 300.2695 |
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| SMILES | Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(cc1)C(O)=O |
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| Structure | 
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