| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50026559 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_61442 |
|---|
| IC50 | 13000±n/a nM |
|---|
| Citation |  de Paulis, T; Kumar, Y; Johansson, L; Rämsby, S; Florvall, L; Hall, H; Angeby-Möller, K; Ogren, SO Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides. J Med Chem28:1263-9 (1985) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50026559 |
|---|
| n/a |
|---|
| Name | BDBM50026559 |
|---|
| Synonyms: | 3-Bromo-2-ethoxy-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-methoxy-benzamide | CHEMBL282463 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H25BrN2O3 |
|---|
| Mol. Mass. | 385.296 |
|---|
| SMILES | CCOc1c(Br)ccc(OC)c1C(=O)NC[C@@H]1CCCN1CC |
|---|
| Structure | 
|
|---|
Search and Browse
