| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
|---|
| Ligand | BDBM50024808 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_152596 |
|---|
| Ki | 1429000±n/a nM |
|---|
| Citation |  Grunewald, GL; Markovich, KM; Sall, DJ Binding orientation of amphetamine and norfenfluramine analogues in the benzonorbornene and benzobicyclo[3.2.1]octane ring systems at the active site of phenylethanolamine N-methyltransferase (PNMT) J Med Chem30:2191-208 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Phenylethanolamine N-methyltransferase |
|---|
| Name: | Phenylethanolamine N-methyltransferase |
|---|
| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 30916.97 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 283 |
|---|
| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
|
|
|
|---|
| BDBM50024808 |
|---|
| n/a |
|---|
| Name | BDBM50024808 |
|---|
| Synonyms: | 1-Trifluoromethyl-6,7,8,9-tetrahydro-5H-5,8-methano-benzocyclohepten-10-ylamine | CHEMBL70384 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14F3N |
|---|
| Mol. Mass. | 241.2522 |
|---|
| SMILES | N[C@H]1C2CCC1c1cccc(c1C2)C(F)(F)F |TLB:7:6:1:4.3,THB:10:11:1:4.3,0:1:11.6.12:4.3| |
|---|
| Structure | 
|
|---|
Search and Browse
