Ki Summary

Reaction Details

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Target

N-acetyllactosaminide alpha-1,3-galactosyltransferase

Ligand

BDBM50367549

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_219109

165000±n/a nM

Citation

Vaghefi, MM; Bernacki, RJ; Dalley, NK; Wilson, BE; Robins, RK Synthesis of glycopyranosylphosphonate analogues of certain natural nucleoside diphosphate sugars as potential inhibitors of glycosyltransferases. J Med Chem30:1383-91 (1987) [PubMed]

More Info.:

Get all data from this article, Assay Method

N-acetyllactosaminide alpha-1,3-galactosyltransferase

Name:

N-acetyllactosaminide alpha-1,3-galactosyltransferase

Synonyms:

GGTA1_MOUSE | Galactosyltransferase | Ggta-1 | Ggta1 | UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase

Type:

PROTEIN

Mol. Mass.:

46474.57

Organism:

Mus musculus

Description:

ChEMBL_219109

Residue:

394

Sequence:

MITMLQDLHVNKISMSRSKSETSLPSSRSGSQEKIMNVKGKVILLMLIVSTVVVVFWEYV
NRIPEVGENRWQKDWWFPSWFKNGTHSYQEDNVEGRREKGRNGDRIEEPQLWDWFNPKNR
PDVLTVTPWKAPIVWEGTYDTALLEKYYATQKLTVGLTVFAVGKYIEHYLEDFLESADMY
FMVGHRVIFYVMIDDTSRMPVVHLNPLHSLQVFEIRSEKRWQDISMMRMKTIGEHILAHI
QHEVDFLFCMDVDQVFQDNFGVETLGQLVAQLQAWWYKASPEKFTYERRELSAAYIPFGE
GDFYYHAAIFGGTPTHILNLTRECFKGILQDKKHDIEAQWHDESHLNKYFLFNKPTKILS
PEYCWDYQIGLPSDIKSVKVAWQTKEYNLVRNNV

BDBM50367549

n/a

Name

BDBM50367549

Synonyms:

CHEMBL604428

Type

Small organic molecule

Emp. Form.

C15H24N2O16P2

Mol. Mass.

550.3024

SMILES

OC[C@H]1OC([C@H](O)[C@@H](O)[C@@H]1O)P(O)(=O)OP(O)(=O)OC[C@H]1OC([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r|

Structure