| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
|---|
| Ligand | BDBM50029050 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_39325 (CHEMBL653363) |
|---|
| Ki | 3000±n/a nM |
|---|
| Citation |  Adejare, A; Gusovsky, F; Padgett, W; Creveling, CR; Daly, JW; Kirk, KL Syntheses and adrenergic activities of ring-fluorinated epinephrines. J Med Chem31:1972-7 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-1 adrenergic receptor |
|---|
| Name: | Beta-1 adrenergic receptor |
|---|
| Synonyms: | ADRB1 | Adrenergic receptor | adrenergic Beta1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50540.48 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73 |
|---|
| Residue: | 467 |
|---|
| Sequence: | MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAG
MGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVC
TVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDE
DEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
|
|
|
|---|
| BDBM50029050 |
|---|
| n/a |
|---|
| Name | BDBM50029050 |
|---|
| Synonyms: | (-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol | (-)-adrenaline | (R)-(-)-adrenaline | (R)-adrenaline | 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol | Adrenalin | CHEMBL679 | EPINEPHRINE | adrenaline | levoepinephrine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H13NO3 |
|---|
| Mol. Mass. | 183.2044 |
|---|
| SMILES | CNC[C@H](O)c1ccc(O)c(O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
