| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Polyunsaturated fatty acid 5-lipoxygenase |
|---|
| Ligand | BDBM85245 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_3966 |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Clemence, F; Le Martret, O; Delevallee, F; Benzoni, J; Jouanen, A; Jouquey, S; Mouren, M; Deraedt, R 4-Hydroxy-3-quinolinecarboxamides with antiarthritic and analgesic activities. J Med Chem31:1453-62 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Polyunsaturated fatty acid 5-lipoxygenase |
|---|
| Name: | Polyunsaturated fatty acid 5-lipoxygenase |
|---|
| Synonyms: | Alox5 | Arachidonate 5-lipoxygenase | LOX5_RAT |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 78082.31 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1432947 |
|---|
| Residue: | 673 |
|---|
| Sequence: | MPSYTVTVATGSQWFAGTDDYIYLSLIGSAGCSEKHLLDKAFYNDFERGGRDSYDVTVDE
ELGEIYLVKIEKRKYRLHDDWYLKYITLKTPHDYIEFPCYRWITGEGEIVLRDGCAKLAR
DDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLN
YSKAMENLFINRFMHMFQSSWHDFADFEKIFVKISNTISERVKNHWQEDLMFGYQFLNGC
NPVLIKRCTELPKKLPVTTEMVECSLERQLSLEQEVQEGNIFIVDYELLDGIDANKTDPC
THQFLAAPICLLYKNLANKIVPIAIQLNQTPGEKNPIFLPTDSKYDWLLAKIWVRSSDFH
IHQTITHLLRTHLVSEVFGIAMYRQLPAVHPLFKLLVAHVRFTIAINTKAREQLNCEYGL
FDKANATGGGGHVQMVQRAVQDLTYSSLCFPEAIKARGMDNTEDIPYYFYRDDGLLVWEA
IQSFTTEVVSIYYEDDQVVEEDQELQDFVKDVYVYGMRGRKASGFPKSIKSREKLSEYLT
VVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWH
LGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMIRFRKNLEAIVSVIAERNKNKKLPYY
YLSPDRIPNSVAI
|
|
|
|---|
| BDBM85245 |
|---|
| n/a |
|---|
| Name | BDBM85245 |
|---|
| Synonyms: | CAS_36322-90-4 | NSC_4856 | Piroxicam |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13N3O4S |
|---|
| Mol. Mass. | 331.346 |
|---|
| SMILES | CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |t:12| |
|---|
| Structure | 
|
|---|
Search and Browse
