Ki Summary

Reaction Details

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Target

Muscarinic receptor M1

Ligand

BDBM50296314

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_140160

0.200000±n/a nM

Citation

Rzeszotarski, WJ; McPherson, DW; Ferkany, JW; Kinnier, WJ; Noronha-Blob, L; Kirkien-Rzeszotarski, A Affinity and selectivity of the optical isomers of 3-quinuclidinyl benzilate and related muscarinic antagonists. J Med Chem31:1463-6 (1988) [PubMed]

More Info.:

Get all data from this article, Assay Method

Muscarinic receptor M1

Name:

Muscarinic receptor M1

Synonyms:

Muscarinic acetylcholine receptor M1

Type:

PROTEIN

Mol. Mass.:

15022.43

Organism:

Bos taurus

Description:

ChEMBL_140161

Residue:

139

Sequence:

ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYS
WKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKG
RERAGKGQKPRGKEQLAKR

BDBM50296314

n/a

Name

BDBM50296314

Synonyms:

(3R)-1-Azabicyclo[2.2.2]oct-3-yl9H-xanthene-9-carboxylate | CHEMBL549577

Type

Small organic molecule

Emp. Form.

C21H21NO3

Mol. Mass.

335.3963

SMILES

O=C(O[C@H]1CN2CCC1CC2)C1c2ccccc2Oc2ccccc12 |r,wD:3.2,(-1.78,.66,;-3.13,-.09,;-3.15,-1.63,;-1.81,-2.4,;-1.81,-3.94,;-.48,-4.7,;.85,-3.94,;.85,-2.4,;-.48,-1.62,;-.06,-2.86,;-1.11,-3.21,;-4.45,.7,;-5.79,-.04,;-5.82,-1.58,;-7.17,-2.33,;-8.5,-1.53,;-8.47,.02,;-7.11,.76,;-7.09,2.3,;-5.74,3.04,;-5.72,4.57,;-4.38,5.32,;-3.05,4.53,;-3.07,2.99,;-4.42,2.25,)|

Structure