| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thymidine kinase |
|---|
| Ligand | BDBM50013099 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_207840 |
|---|
| EC50 | 3000±n/a nM |
|---|
| Citation |  Focher, F; Hildebrand, C; Freese, S; Ciarrocchi, G; Noonan, T; Sangalli, S; Brown, N; Spadari, S; Wright, G N2-phenyldeoxyguanosine: a novel selective inhibitor of herpes simplex thymidine kinase. J Med Chem31:1496-500 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thymidine kinase |
|---|
| Name: | Thymidine kinase |
|---|
| Synonyms: | KITH_HHV1S | TK | Thymidine kinase | UL23 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40883.42 |
|---|
| Organism: | Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1) |
|---|
| Description: | ChEMBL_213 |
|---|
| Residue: | 376 |
|---|
| Sequence: | MASYPGHQHASAFDQAARSRGHSNRRTALRPRRQQEATEVRPEQKMPTLLRVYIDGPHGM
GKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVV
MTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMG
SMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYG
LLANTVRYLQGGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAP
NGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMIQTHVTTPGSIPT
ICDLARTFAREMGEAN
|
|
|
|---|
| BDBM50013099 |
|---|
| n/a |
|---|
| Name | BDBM50013099 |
|---|
| Synonyms: | 2-(3-Ethyl-phenylamino)-1,9-dihydro-purin-6-one | CHEMBL35886 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H13N5O |
|---|
| Mol. Mass. | 255.2752 |
|---|
| SMILES | CCc1cccc(Nc2nc3nc[nH]c3c(=O)[nH]2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
