| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50023801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_61437 |
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| IC50 | 7.7±n/a nM |
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| Citation |  Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Substituted benzamides. 1. Potential nondopaminergic antagonists of chemotherapy-induced nausea and emesis. J Med Chem31:1548-58 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50023801 |
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| n/a |
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| Name | BDBM50023801 |
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| Synonyms: | 3-Amino-2-chloro-11-ethyl-6,7,8,9,10,11,12,13,14,15-decahydro-5-oxa-11,15-diaza-benzocyclotetradecen-16-one | CHEMBL432681 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H26ClN3O2 |
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| Mol. Mass. | 339.86 |
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| SMILES | CCN1CCCCCOc2cc(N)c(Cl)cc2C(=O)NCCC1 |
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| Structure | 
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