Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPhenylethanolamine N-methyltransferase
LigandBDBM50367283
Substrate/Competitorn/a
Meas. Tech.ChEBML_152563
Ki>3000000±n/a nM
Citation Ye, QHGrunewald, GL Conformationally restricted and conformationally defined tyramine analogues as inhibitors of phenylethanolamine N-methyltransferase. J Med Chem32:478-86 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Phenylethanolamine N-methyltransferase
Name:Phenylethanolamine N-methyltransferase
Synonyms:Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase
Type:Enzyme
Mol. Mass.:30916.97
Organism:Bos taurus (bovine)
Description:n/a
Residue:283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50367283
n/a
NameBDBM50367283
Synonyms:CHEMBL292281
TypeSmall organic molecule
Emp. Form.C11H13NO
Mol. Mass.175.227
SMILESN[C@@H]1CC2CC1c1c2cccc1O |TLB:0:1:4:6.7,THB:11:6:4:1.2,8:7:4:1.2|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: