| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50017070 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_146883 |
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| IC50 | >10000±n/a nM |
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| Citation |  Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Synthesis, opioid receptor binding profile, and antinociceptive activity of 1-azaspiro[4.5]decan-10-yl amides. J Med Chem32:1259-65 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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|
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| BDBM50017070 |
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| n/a |
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| Name | BDBM50017070 |
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| Synonyms: | 4-Bromo-N-isobutyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide | CHEMBL22458 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31BrN2O |
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| Mol. Mass. | 407.388 |
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| SMILES | CC(C)CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)cc1 |
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| Structure | 
|
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