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TargetAminopeptidase B
LigandBDBM50017479
Substrate/Competitorn/a
Meas. Tech.ChEMBL_35355 (CHEMBL647937)
Ki 8800±n/a nM
Citation Harbeson, SLRich, DH Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. J Med Chem32:1378-92 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Aminopeptidase B
Name:Aminopeptidase B
Synonyms:AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep
Type:PROTEIN
Mol. Mass.:72609.93
Organism:Rattus norvegicus
Description:ChEMBL_1344423
Residue:650
Sequence:
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50017479
n/a
NameBDBM50017479
Synonyms:2-(5,9-Diamino-2-methyl-4-oxo-nonanoylamino)-3-phenyl-propionic acid | CHEMBL28708
TypeSmall organic molecule
Emp. Form.C19H29N3O4
Mol. Mass.363.4513
SMILESCC(CC(=O)[C@@H](N)CCCCN)C(=O)NC(Cc1ccccc1)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: