| Reaction Details |
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 | Report a problem with these data |
| Target | Aminopeptidase B |
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| Ligand | BDBM50017483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_35354 |
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| Ki | 36000±n/a nM |
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| Citation |  Harbeson, SL; Rich, DH Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. J Med Chem32:1378-92 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminopeptidase B |
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| Name: | Aminopeptidase B |
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| Synonyms: | AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep |
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| Type: | PROTEIN |
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| Mol. Mass.: | 72609.93 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1344423 |
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| Residue: | 650 |
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| Sequence: | MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
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| BDBM50017483 |
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| n/a |
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| Name | BDBM50017483 |
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| Synonyms: | 5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid [2-methyl-1-(3-methyl-butylcarbamoyl)-propyl]-amide | CHEMBL284228 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H43N3O3 |
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| Mol. Mass. | 445.6379 |
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| SMILES | CC(C)CCNC(=O)[C@@H](NC(=O)[C@H](CC(=O)[C@@H](N)CC(C)C)Cc1ccccc1)C(C)C |
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| Structure | 
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