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TargetAminopeptidase B
LigandBDBM50017484
Substrate/Competitorn/a
Meas. Tech.ChEBML_35354
Ki 2000±n/a nM
Citation Harbeson, SLRich, DH Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. J Med Chem32:1378-92 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Aminopeptidase B
Name:Aminopeptidase B
Synonyms:AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep
Type:PROTEIN
Mol. Mass.:72609.93
Organism:Rattus norvegicus
Description:ChEMBL_1344423
Residue:650
Sequence:
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50017484
n/a
NameBDBM50017484
Synonyms:5,9-Diamino-2-methyl-4-oxo-nonanoic acid | CHEMBL282212
TypeSmall organic molecule
Emp. Form.C10H20N2O3
Mol. Mass.216.2774
SMILESCC(CC(=O)[C@@H](N)CCCCN)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: