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TargetAminopeptidase B
LigandBDBM50008434
Substrate/Competitorn/a
Meas. Tech.ChEBML_35354
Ki 170±n/a nM
Citation Harbeson, SLRich, DH Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. J Med Chem32:1378-92 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Aminopeptidase B
Name:Aminopeptidase B
Synonyms:AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep
Type:PROTEIN
Mol. Mass.:72609.93
Organism:Rattus norvegicus
Description:ChEMBL_1344423
Residue:650
Sequence:
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50008434
n/a
NameBDBM50008434
Synonyms:5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid | CHEMBL140459
TypeSmall organic molecule
Emp. Form.C16H23NO3
Mol. Mass.277.3587
SMILESCC(C)C[C@H](N)C(=O)CC(Cc1ccccc1)C(O)=O
Structure
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