| Reaction Details |
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 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
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| Ligand | BDBM50018237 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_152590 |
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| Ki | 8±n/a nM |
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| Citation |  Girard, GR; Bondinell, WE; Hillegass, LM; Holden, KG; Pendleton, RG; Uzinskas, I Tetrahydrothiadiazoloisoquinolines: synthesis and inhibition of phenylethanolamine-N-methyltransferase. J Med Chem32:1566-71 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phenylethanolamine N-methyltransferase |
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| Name: | Phenylethanolamine N-methyltransferase |
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| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
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| Type: | Enzyme |
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| Mol. Mass.: | 30916.97 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 283 |
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| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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| BDBM50018237 |
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| n/a |
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| Name | BDBM50018237 |
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| Synonyms: | 6,7,8,9-Tetrahydro-3-thia-1,2,8-triaza-cyclopenta[a]naphthalene; hydrochloride | CHEMBL541538 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9N3S |
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| Mol. Mass. | 191.253 |
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| SMILES | C1Cc2ccc3snnc3c2CN1 |
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| Structure | 
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