| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50018420 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29628 |
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| Ki | 0.655000±n/a nM |
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| Citation |  Jacobson, KA; Kiriasis, L; Barone, S; Bradbury, BJ; Kammula, U; Campagne, JM; Secunda, S; Daly, JW; Neumeyer, JL; Pfleiderer, W Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. J Med Chem32:1873-9 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50018420 |
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| n/a |
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| Name | BDBM50018420 |
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| Synonyms: | 8-Cyclopentyl-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one | CHEMBL292904 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24N4OS |
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| Mol. Mass. | 320.453 |
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| SMILES | CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C1CCCC1 |
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| Structure | 
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