| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interstitial collagenase |
|---|
| Ligand | BDBM50367936 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_49509 |
|---|
| pH | 7.5±n/a |
|---|
| Ki | 120000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Kortylewicz, ZP; Galardy, RE Phosphoramidate peptide inhibitors of human skin fibroblast collagenase. J Med Chem33:263-73 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Interstitial collagenase |
|---|
| Name: | Interstitial collagenase |
|---|
| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54010.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P03956 |
|---|
| Residue: | 469 |
|---|
| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
|
|
|
|---|
| BDBM50367936 |
|---|
| n/a |
|---|
| Name | BDBM50367936 |
|---|
| Synonyms: | CHEMBL1744415 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H40N3O8P |
|---|
| Mol. Mass. | 637.6609 |
|---|
| SMILES | CCOP([O-])(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(Cc1ccccc1)C([O-])=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
