| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50367950 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_37835 |
|---|
| IC50 | 41000±n/a nM |
|---|
| Citation |  Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity. J Med Chem33:2883-91 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2_CANLF |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46593.67 |
|---|
| Organism: | Canis familiaris |
|---|
| Description: | ChEMBL_56504 |
|---|
| Residue: | 415 |
|---|
| Sequence: | MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIAR
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRF
HAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNS
RSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50367950 |
|---|
| n/a |
|---|
| Name | BDBM50367950 |
|---|
| Synonyms: | CHEMBL1192069 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H26N4O5S |
|---|
| Mol. Mass. | 446.52 |
|---|
| SMILES | CS(=O)(=O)Nc1ccc(OC[C@H](O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
