Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Kappa-type opioid receptor | ||
Ligand | BDBM50013625 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_146526 (CHEMBL753838) | ||
Ki | 65±n/a nM | ||
Citation | Portoghese, PS; Sultana, M; Takemori, AE Design of peptidomimetic delta opioid receptor antagonists using the message-address concept. J Med Chem33:1714-20 (1990) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Kappa-type opioid receptor | |||
Name: | Kappa-type opioid receptor | ||
Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 42744.99 | ||
Organism: | Cavia porcellus (domestic guinea pig) | ||
Description: | P41144 | ||
Residue: | 380 | ||
Sequence: |
| ||
BDBM50013625 | |||
n/a | |||
Name | BDBM50013625 | ||
Synonyms: | 22-cyclopropylmethyl-11-methyl-(1S,2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol | 22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl2H2O) | 22-cyclopropylmethyl-11-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol | ||
Type | Small organic molecule | ||
Emp. Form. | C27H28N2O3 | ||
Mol. Mass. | 428.5228 | ||
SMILES | Cn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2ccccc12)ccc4O |TLB:28:7:18:10.16.15,5:6:18:10.16.15| | ||
Structure |