| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM55121 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_60517 |
|---|
| IC50 | 800±n/a nM |
|---|
| Citation |  Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist. J Med Chem33:1756-64 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM55121 |
|---|
| n/a |
|---|
| Name | BDBM55121 |
|---|
| Synonyms: | 3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-aminoethyl)pyrocatechol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | Dopamine | MLS000069419 | SMR000059081 | cid_65340 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H11NO2 |
|---|
| Mol. Mass. | 153.1784 |
|---|
| SMILES | NCCc1ccc(O)c(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
