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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50001714 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_146692 | ||
| IC50 | 1.4±n/a nM | ||
| Citation |  Klein, P; Nelson, WL; Yao, YH; Simon, EJ Electrophilic alpha-methylene-gamma-lactone and isothiocyanate opioid ligands related to etorphine. J Med Chem33:2286-96 (1990) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 45038.37 | ||
| Organism: | CALF | ||
| Description: | OPIATE Mu 2 0 CALF::P79350 | ||
| Residue: | 401 | ||
| Sequence: |
| ||
| BDBM50001714 | |||
| n/a | |||
| Name | BDBM50001714 | ||
| Synonyms: | 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol | 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol(diprenorphine) | 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10-trien-16-yl]-2-propanol | CHEMBL281786 | DIPRENORPHINE-HCl | Diprenorphine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H35NO4 | ||
| Mol. Mass. | 425.5604 | ||
| SMILES | CO[C@]12CC[C@@]3(C[C@@H]1C(C)(C)O)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |THB:8:7:22.21:4.3| | ||
| Structure | 
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