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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50013768 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_146692 | ||
| IC50 | 34±n/a nM | ||
| Citation |  Klein, P; Nelson, WL; Yao, YH; Simon, EJ Electrophilic alpha-methylene-gamma-lactone and isothiocyanate opioid ligands related to etorphine. J Med Chem33:2286-96 (1990) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 45038.37 | ||
| Organism: | CALF | ||
| Description: | OPIATE Mu 2 0 CALF::P79350 | ||
| Residue: | 401 | ||
| Sequence: |
| ||
| BDBM50013768 | |||
| n/a | |||
| Name | BDBM50013768 | ||
| Synonyms: | 3-O-(tert-Butyldimethylsilyl)-6,14-endo-etheno-7alpha-(3-carboxy-3-n-butenyl) tetrahydrooripavine gama-Lactone | CHEMBL3038193 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H41NO5Si | ||
| Mol. Mass. | 535.7464 | ||
| SMILES | [H][C@@]1(CC(=C)C(=O)O1)[C@@]1([H])C[C@]23C=C[C@]1(OC)[C@]1([H])Oc4c5c(C[C@@]2([H])N(C)CC[C@@]315)ccc4O[Si](C)(C)C(C)(C)C |wU:30.32,8.9,17.19,wD:11.12,14.16,1.0,24.27,c:13,TLB:27:26:11:21.22.23,(13.98,-17.19,;14,-15.33,;15.23,-16.24,;14.74,-17.7,;15.83,-18.78,;13.2,-17.69,;12.42,-19.02,;12.73,-16.21,;14,-13.79,;15.6,-14.73,;15.35,-13.04,;15.37,-11.5,;14,-11.47,;13.99,-12.85,;12.68,-12.99,;11.33,-13.74,;10.02,-12.96,;12.71,-11.47,;11.21,-11.81,;11.96,-9.97,;12.71,-8.41,;14.04,-9.19,;15.37,-8.41,;16.7,-9.2,;16.7,-10.74,;17.1,-12.23,;18.04,-11.52,;19.36,-12.29,;17.78,-9.62,;15.13,-9.62,;14.04,-10.72,;15.37,-6.87,;14.04,-6.1,;12.71,-6.89,;11.37,-6.1,;11.36,-4.56,;9.82,-4.55,;12.9,-4.56,;11.35,-3.02,;10.02,-2.25,;12.68,-2.24,;11.75,-1.53,)| | ||
| Structure | 
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