| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50010059 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_61769 |
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| IC50 | >1000±n/a nM |
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| Citation |  Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Naphthosultam derivatives: a new class of potent and selective 5-HT2 antagonists. J Med Chem34:2477-83 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50010059 |
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| n/a |
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| Name | BDBM50010059 |
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| Synonyms: | 2-{3-[4-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide | CHEMBL309408 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N4O4S2 |
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| Mol. Mass. | 496.602 |
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| SMILES | O=S1(=O)N=C(N2CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc12 |t:3| |
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| Structure | 
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