Reaction Details |
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Target | Adenosine receptor A1 |
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Ligand | BDBM50009686 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_29468 |
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Ki | 530±n/a nM |
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Citation | Thompson, RD; Secunda, S; Daly, JW; Olsson, RA N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. J Med Chem34:2877-82 (1991) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Adenosine receptor A1 |
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Name: | Adenosine receptor A1 |
Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
Type: | Protein |
Mol. Mass.: | 36704.13 |
Organism: | Rattus norvegicus (rat) |
Description: | n/a |
Residue: | 326 |
Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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BDBM50009686 |
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n/a |
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Name | BDBM50009686 |
Synonyms: | (2-Chloro-9-methyl-9H-purin-6-yl)-cyclopentyl-amine | CHEMBL88788 |
Type | Small organic molecule |
Emp. Form. | C11H14ClN5 |
Mol. Mass. | 251.715 |
SMILES | Cn1cnc2c(NC3CCCC3)nc(Cl)nc12 |
Structure |
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