| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50001039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_146540 |
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| Ki | 3±n/a nM |
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| Citation |  Carroll, FI; Abraham, P; Parham, K; Bai, X; Zhang, X; Brine, GA; Mascarella, SW; Martin, BR; May, EL; Sauss, C Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors. J Med Chem35:2812-8 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44503.11 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
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| Residue: | 398 |
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| Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50001039 |
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| n/a |
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| Name | BDBM50001039 |
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| Synonyms: | 6,11-Dimethyl-3-(1-methyl-allyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | CHEMBL2367796 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H25NO |
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| Mol. Mass. | 271.3972 |
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| SMILES | [H][C@](C)(C=C)N1CC[C@@]2(C)[C@@H](C)[C@@]1([H])Cc1ccc(O)cc21 |TLB:1:5:10:21.14.15,THB:20:21:10:5.7.6| |
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| Structure | 
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