| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
|---|
| Ligand | BDBM50003055 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_143848 |
|---|
| Kd | 1.2±n/a nM |
|---|
| Citation |  Reymond, MT; Delmas, L; Koerber, SC; Brown, MR; Rivier, JE Truncated, branched, and/or cyclic analogues of neuropeptide Y: importance of the pancreatic peptide fold in the design of specific Y2 receptor ligands. J Med Chem35:3653-9 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 2 |
|---|
| Name: | Neuropeptide Y receptor type 2 |
|---|
| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42734.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
|
|
|
|---|
| BDBM50003055 |
|---|
| n/a |
|---|
| Name | BDBM50003055 |
|---|
| Synonyms: | CHEMBL414947 | Tyr-Pro-Ser-Lys-Pro-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C110H174N34O26 |
|---|
| Mol. Mass. | 2388.7708 |
|---|
| SMILES | CCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
