Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50368425 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_157563 |
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Ki | 1.3±n/a nM |
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Citation | Rich, DH; Prasad, JV; Sun, CQ; Green, J; Mueller, R; Houseman, K; MacKenzie, D; Malkovsky, M New hydroxyethylamine HIV protease inhibitors that suppress viral replication. J Med Chem35:3803-12 (1992) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50368425 |
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n/a |
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Name | BDBM50368425 |
Synonyms: | CHEMBL1790885 | CHEMBL3349495 |
Type | Small organic molecule |
Emp. Form. | C47H70N8O11 |
Mol. Mass. | 923.1057 |
SMILES | [H][C@@](O)(CN1CCCC1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCc1ccccc1)C(=O)OC)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(C)=O |
Structure |
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