| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50002143 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_39323 |
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| Ki | 5000±n/a nM |
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| Citation |  Meurer, LC; Tolman, RL; Chapin, EW; Saperstein, R; Vicario, PP; Zrada, MM; MacCoss, M Synthesis and hypoglycemic activity of substituted 8-(1-piperazinyl)imidazo[1,2-a]pyrazines. J Med Chem35:3845-57 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | Adrenergic receptor | adrenergic Beta1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50540.48 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73 |
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| Residue: | 467 |
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| Sequence: | MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAG
MGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVC
TVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDE
DEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
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| BDBM50002143 |
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| n/a |
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| Name | BDBM50002143 |
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| Synonyms: | 3-Ethyl-8-piperazin-1-yl-imidazo[1,2-a]pyrazine; 2M.hydrochloride | CHEMBL538537 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H17N5 |
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| Mol. Mass. | 231.2969 |
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| SMILES | CCc1cnc2c(nccn12)N1CCNCC1 |
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| Structure | 
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