| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50002217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201877 |
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| Ki | 3±n/a nM |
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| Citation |  Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK Novel piperidine sigma receptor ligands as potential antipsychotic drugs. J Med Chem35:4344-61 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25246.51 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | O55242 |
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| Residue: | 223 |
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| Sequence: | MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPS
TLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
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| BDBM50002217 |
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| n/a |
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| Name | BDBM50002217 |
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| Synonyms: | 2-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-1-(4-fluoro-phenyl)-ethanone | CHEMBL136768 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21F2NO |
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| Mol. Mass. | 329.3836 |
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| SMILES | Fc1ccc(CN2CCC(CC(=O)c3ccc(F)cc3)CC2)cc1 |
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| Structure | 
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