| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50002290 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58197 |
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| IC50 | 114±n/a nM |
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| Citation |  Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK Novel piperidine sigma receptor ligands as potential antipsychotic drugs. J Med Chem35:4344-61 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 50957.64 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P61168 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50002290 |
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| n/a |
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| Name | BDBM50002290 |
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| Synonyms: | 1-Benzyl-4-[2-(4-fluoro-phenoxy)-ethyl]-piperidine; hydrochloride;0.2hydrate | CHEMBL540585 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24FNO |
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| Mol. Mass. | 313.4091 |
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| SMILES | Fc1ccc(OCCC2CCN(Cc3ccccc3)CC2)cc1 |
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| Structure | 
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