| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50000496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_37542 |
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| Ki | >100000±n/a nM |
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| Citation |  Macchia, B; Balsamo, A; Breschi, MC; Lapucci, A; Lucacchini, A; Macchia, F; Manera, C; Martinelli, A; Martini, C; Martinotti, E Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic receptors. J Med Chem35:1009-18 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
|
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|
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| BDBM50000496 |
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| n/a |
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| Name | BDBM50000496 |
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| Synonyms: | 4-(3-Hydroxy-piperidin-3-yl)-benzene-1,2-diol | CHEMBL7278 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H15NO3 |
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| Mol. Mass. | 209.2417 |
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| SMILES | Oc1ccc(cc1O)C1(O)CCCNC1 |
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| Structure | 
|
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