| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil elastase |
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| Ligand | BDBM50005910 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_63643 (CHEMBL675354) |
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| IC50 | 17000±n/a nM |
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| Citation |  Zembower, DE; Kam, CM; Powers, JC; Zalkow, LH Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G. J Med Chem35:1597-605 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutrophil elastase |
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| Name: | Neutrophil elastase |
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| Synonyms: | Bone marrow serine protease | Chymotrypsin | Coagulation factor X | ELA2 | ELANE | ELNE_HUMAN | Elastase | Elastase-2 | HLE | Human leukocyte elastase | Leukocyte elastase | Leukocyte elastase (HLE) | Medullasin | Neutrophil elastase | Neutrophil elastase (HNE) | Neutrophil elastase (NE) | PMN elastase | Thrombin | Trypsin |
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| Type: | Enzyme |
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| Mol. Mass.: | 28532.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08246 |
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| Residue: | 267 |
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| Sequence: | MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLI
APNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVI
LQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL
CRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVN
WIDSIIQRSEDNPCPHPRDPDPASRTH
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| BDBM50005910 |
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| n/a |
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| Name | BDBM50005910 |
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| Synonyms: | 3-Dibromomethyl-1,6,8-trimethoxy-anthraquinone | CHEMBL39204 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14Br2O5 |
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| Mol. Mass. | 470.109 |
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| SMILES | COc1cc(OC)c2C(=O)c3c(OC)cc(cc3C(=O)c2c1)C(Br)Br |
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| Structure | 
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