| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM82247 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_62775 |
|---|
| Ki | 768±n/a nM |
|---|
| Citation |  Foulon, C; Kung, MP; Kung, HF Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'- propenyl)-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand. J Med Chem36:1499-500 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 49540.58 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P19020 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
|
|
|
|---|
| BDBM82247 |
|---|
| n/a |
|---|
| Name | BDBM82247 |
|---|
| Synonyms: | 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390) | CAS_87134-87-0 | CHEMBL2158641 | CHEMBL62 | SCH 23388 | SCH 23390 | SCH 23390 (R-enantiomer) | SCH 23390,R(+) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18ClNO |
|---|
| Mol. Mass. | 287.784 |
|---|
| SMILES | CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
