| Reaction Details |
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 | Report a problem with these data |
| Target | Thermolysin |
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| Ligand | BDBM50044226 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210395 |
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| IC50 | 7±n/a nM |
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| Citation |  Patchett, AA Excursions in drug discovery. J Med Chem36:2051-8 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Thermolysin |
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| Name: | Thermolysin |
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| Synonyms: | THER_BACTH | npr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60097.54 |
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| Organism: | Bacillus thermoproteolyticus |
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| Description: | ChEMBL_1468794 |
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| Residue: | 548 |
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| Sequence: | MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEEL
VYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDG
TLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVY
VNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVG
VGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDA
PAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQ
TFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEI
GEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGG
THYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQ
AFDAVGVK
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| BDBM50044226 |
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| n/a |
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| Name | BDBM50044226 |
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| Synonyms: | 1-hydroxy-1-phenylethyl-phosphinoylamino]-propionyl-pyrrolidine-2-carboxylic acid | CHEMBL62955 | Compound 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H23N2O5P |
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| Mol. Mass. | 354.338 |
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| SMILES | CC(NP(O)(=O)CCc1ccccc1)C(=O)N1CCCC1C(O)=O |
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| Structure | 
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