| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50006705 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29423 |
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| Ki | >100000±n/a nM |
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| Citation |  Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E Adenosine A1 antagonists. 3. Structure-activity relationships on amelioration against scopolamine- or N6-((R)-phenylisopropyl)adenosine-induced cognitive disturbance. J Med Chem36:2508-18 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36501.39 |
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| Organism: | GUINEA PIG |
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| Description: | ADENOSINE A1 ADORA1 GUINEA PIG::P47745 |
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| Residue: | 326 |
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| Sequence: | MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPEPPIDEDLPEEKVDD
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| BDBM50006705 |
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| n/a |
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| Name | BDBM50006705 |
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| Synonyms: | 1,3,7-Trimethyl-8-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione | CHEMBL27203 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N4O5 |
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| Mol. Mass. | 386.4018 |
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| SMILES | COc1cc(\C=C\c2nc3n(C)c(=O)n(C)c(=O)c3n2C)cc(OC)c1OC |
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| Structure | 
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