| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50040284 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201715 |
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| IC50 | 21±n/a nM |
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| Citation |  Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity. J Med Chem36:2542-51 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50040284 |
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| n/a |
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| Name | BDBM50040284 |
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| Synonyms: | 3-Chloro-6-methylamino-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol | CHEMBL87321 | trans-3-Chloro-6-methylamino-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClNO |
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| Mol. Mass. | 287.784 |
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| SMILES | CNC1CC(c2ccccc2)c2cc(O)c(Cl)cc2C1 |
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| Structure | 
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