| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50042466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_98894 (CHEMBL703402) |
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| Ki | 260±n/a nM |
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| Citation |  Trybulski, EJ; Zhang, J; Kramss, RH; Mangano, RM The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives. J Med Chem36:3533-41 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51555.53 |
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| Organism: | RAT |
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| Description: | P10980 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50042466 |
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| n/a |
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| Name | BDBM50042466 |
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| Synonyms: | 1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin-2-one | CHEMBL442206 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H18N2O |
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| Mol. Mass. | 194.2734 |
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| SMILES | CC1CCN(CC#CCN(C)C)C1=O |
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| Structure | 
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