| Reaction Details |
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 | Report a problem with these data |
| Target | Ribonucleoside-diphosphate reductase large subunit |
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| Ligand | BDBM50368751 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195540 (CHEMBL800987) |
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| IC50 | 9000±n/a nM |
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| Citation |  Fisher, A; Yang, FD; Rubin, H; Cooperman, BS R2 C-terminal peptide inhibition of mammalian and yeast ribonucleotide reductase. J Med Chem36:3859-62 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribonucleoside-diphosphate reductase large subunit |
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| Name: | Ribonucleoside-diphosphate reductase large subunit |
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| Synonyms: | RIR1_MOUSE | Ribonucleoside-diphosphate reductase M1 chain | Ribonucleoside-diphosphate reductase large subunit | Ribonucleoside-diphosphate reductase subunit M1 | Ribonucleotide reductase large subunit | Rrm1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 90210.73 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_195411 |
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| Residue: | 792 |
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| Sequence: | MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA
AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASST
LDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK
EDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL
ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY
LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD
EVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL
GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTPEHTYDFEKLAEVTKVIVRNLNKI
IDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGAL
EASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDWKPLKEKIAKYGIRNSLLIA
PMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQII
ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL
TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKALKEEEEKERNTAAMVCS
LENREECLMCGS
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| BDBM50368751 |
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| n/a |
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| Name | BDBM50368751 |
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| Synonyms: | CHEMBL1790907 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H66N10O18 |
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| Mol. Mass. | 1071.0938 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(C)=O)[C@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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